1	Transformers: Revenge of the Fallen Paramount / DreamWorks $400,686,031	2	Harry Potter and the Half-Blood Prince Warner Bros. Pictures $297,742,596	3	Up Walt Disney Pictures $290,866,563

Rank	Title	Studio	Box Office
1.	Transformers: Revenge of the Fallen	Par / DW	$400,686,031
2.	Harry Potter and the Half-Blood Prince	Warner Bros.	$297,742,596
3.	Up	Disney Pictures	$290,866,563
4.	The Hangover	Warner Bros.	$272,281,640
5.	Star Trek	Paramount	$257,191,845
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6.	Monsters vs. Aliens	DreamWorks	$198,351,526
7.	Ice Age: Dawn of the Dinosaurs	20th Century Fox	$194,254,067
8.	X-Men Origins: Wolverine	20th Century Fox	$179,875,159
9.	Night at the Museum: Battle of the Smithsonian	20th Century Fox	$176,804,099
10.	The Proposal	Disney Pictures	$161,137,964
11.	Fast and Furious	Universal Pictures	$155,064,265
12.	Paul Blart: Mall Cop	Sony Pictures	$146,336,178
13.	Taken	20th Century Fox	$145,000,989
14.	G.I. Joe: The Rise of Cobra	Paramount	$141,301,037
15.	Angels and Demons	Sony Pictures	$133,375,846
16.	Terminator: Salvation	Warner Bros.	$125,320,855
17.	G-Force	Disney Pictures	$115,574,890
18.	Watchmen	Warner Bros.	$107,509,799
19.	District 9	Sony / TriStar	$103,968,663
20.	Public Enemies	Universal Pictures	$97,104,620
21.	Inglourious Basterds	Weinstein	$96,159,036
22.	He's Just Not That Into You	New Line Cinema	$93,953,653
23.	Tyler Perry's Madea Goes to Jail	Lionsgate Films	$90,508,336
24.	The Ugly Truth	Sony Pictures	$87,642,192
25.	Julie & Julia	Sony Pictures	$81,180,763
26.	Knowing	Summit	$79,957,634
27.	Hannah Montana: The Movie	Walt Disney	$79,576,189
28.	Coraline	Focus Features	$75,286,229
29.	Hotel for Dogs	Paramount / DW	$73,034,460
30.	I Love You, Man	DreamWorks	$71,440,011
31.	Obsessed	Sony ScreenGems	$68,261,644
32.	Race to Witch Mountain	Walt Disney	$67,172,594
33.	The Taking of Pelham 1 2 3	Sony Pictures	$65,452,312
34.	Friday, the 13th	New Line Cinema	$65,002,019
35.	17 Again	Warner Bros.	$64,167,069
36.	Bruno	Universal Pictures	$60,054,530
37.	Bride Wars	20th Century Fox	$58,715,510
38.	The Time Traveler's Wife	New Line Cinema	$56,145,191
39.	The Haunting in Connecticut	Lionsgate Films	$55,389,516
40.	Ghosts of Girlfriends Past	New Line Cinema	$55,250,026
41.	Funny People	Universal Pictures	$51,697,440
42.	My Bloody Valentine 3-D	Lionsgate Films	$51,545,952
43.	The Final Destination 3-D	New Line Cinema	$51,372,507
44.	The Land of the Lost	Universal Pictures	$49,438,370
45.	My Sister's Keeper	Warner Bros.	$48,785,374
46.	Underworld: Rise of the Lycans	Sony ScreenGems	$45,802,315
47.	Confessions of a Shopaholic	Walt Disney	$44,277,350
48.	Year One	Sony Pictures	$43,337,279
49.	The Unborn	Universal Pictures	$42,670,410
50.	Drag Me to Hell	Universal Pictures	$42,100,625